Open AccessMEASUREMENT OF BRADYKININ, PROTEIN, Na+, Cl-, K+, AND Zn++ CONCENTRATIONS IN RAT URINE AFTER INTRAPERITONEAL INJECTION OF Tityus serrulatus VENOM
Author(s) -
L.A.F. Ferreira,
M. Bergamasco,
Lúcio Angnes
Publication year - 1996
Publication title -
the journal of venomous animals and toxins/the journal of venomous animals and toxins
Language(s) - English
Resource type - Journals
eISSN - 1678-4936
pISSN - 0104-7930
DOI - 10.1590/s0104-79301996000200008
Subject(s) - venom , scorpion , chemistry , kinin , bradykinin , urine , chromatography , pharmacology , biology , biochemistry , receptor
Experiments were carried out in vivo by injecting Tityus serrulatus crude venom in rats followed by biological assays on the isolated guinea-pig ileum, to show the effects of scorpion venom on kallikrein-kinin system. Our results showed effects such as significant decrease of total kinin rate and a decrease of Zn
, Na
, Cl
and K ions in rat urine 24 and 48 hours after the injection of Tityus serrulatus crude venom
, Na , Cl and K ions in rat urine 24 and 48 hours after the injection of Tityus serrulatus crude venom