Open AccessCybernetic structured modeling of the production of polyhydroxyalkanoates by Alcaligenes Eutrophus
Author(s) -
Luís Ferraz,
Antonio Bonomi,
Rosane Aparecida Moniz Piccoli,
Fernanda M. Kapritchkoff,
Willibaldo Schmidell,
R. C. P. Alli,
Cyro Takano,
M.N. Mattos,
Vinícius Almeida Oliveira,
Valter Fontolan
Publication year - 1999
Publication title -
brazilian journal of chemical engineering/brazilian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 52
eISSN - 1678-4383
pISSN - 0104-6632
DOI - 10.1590/s0104-66321999000200014
Subject(s) - polyhydroxyalkanoates , biochemical engineering , production (economics) , alcaligenes , process engineering , process (computing) , fermentation , computer science , chemistry , bacteria , engineering , food science , biology , pseudomonas , genetics , economics , macroeconomics , operating system
This paper presents a cybernetic structured mathematical model developed for the fermentation step of the process of production of the copolymer of polyhydroxyalkanoates by the bacteria Alcaligenes eutrophus. This process is performed in two different fermentation stages. The first emphasizes the growth of the microorganism in a batch operation without substrates limitations, while in the second, the focus is on copolymer production by a fed-batch operation in the absence of the nitrogen source. This paper presents the results of the treatment of experimental data and of preliminary parameter estimation. The fitting of the proposed model to the experimental data of a standard experiment showed a good agreement