
MATHEMATICAL MODELING, AUTOMATION AND CONTROL OF THE BIOCONVERSION OF SORBITOL TO SORBOSE IN THE VITAMIN C PRODUCTION PROCESS I. MATHEMATICAL MODELING
Author(s) -
Antonio Bonomi,
Anthony Fleury,
E.F.P. Augusto,
M.N. Mattos,
L.R. Magossi
Publication year - 1997
Publication title -
brazilian journal of chemical engineering/brazilian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 52
eISSN - 1678-4383
pISSN - 0104-6632
DOI - 10.1590/s0104-66321997000400001
Subject(s) - sorbose , bioconversion , fermentation , sorbitol , production (economics) , process (computing) , process engineering , mathematics , pulp and paper industry , chemistry , computer science , biochemical engineering , biological system , engineering , food science , biology , fructose , macroeconomics , operating system , economics
In 1990, the Biotechnology and the Control Systems Groups of IPT started developing a system for the control and automation of fermentation processes, applied to the oxidation of sorbitol to sorbose by the bacteria Gluconobacter oxydans, the microbial step of the vitamin C production process, that was chosen as a case study. Initially, a thirteen-parameter model was fitted to represent the batch operation of the system utilizing a nonlinear regression analysis, the flexible polyhedron method. Based on these results, a model for the continuous process (with the same kinetic equations) was constructed and its optimum operating point obtaine