Open AccessStart-up Strategy for Continuous Bioreactors
Author(s) -
Aline Carvalho da Costa,
Enrique Luis Lima,
Tito Lívio Moitinho Alves
Publication year - 1997
Publication title -
brazilian journal of chemical engineering/brazilian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 52
eISSN - 1678-4383
pISSN - 0104-6632
DOI - 10.1590/s0104-66321997000200009
Subject(s) - steady state (chemistry) , bioreactor , dilution , control theory (sociology) , control variable , state variable , dimension (graph theory) , mathematics , optimal control , balance (ability) , mathematical optimization , control (management) , computer science , physics , chemistry , thermodynamics , statistics , medicine , pure mathematics , physical medicine and rehabilitation , organic chemistry , artificial intelligence
- The start-up of continuous bioreactors is solved as an optimal control problem. The choice of the dilution rate as the control variable reduces the dimension of the system by making the use of the global balance equation unnecessary for the solution of the optimization problem. Therefore, for systems described by four or less mass balance equations, it is always possible to obtain an analytical expression for the singular arc as a function of only the state variables. The steady state conditions are shown to satisfy the singular arc expression and, based on this knowledge, a feeding strategy is proposed which leads the reactor from an initial state to the steady state of maximum productivit