Open AccessHipoinsulinemia em alcoolistas com hepatopatia mínima
Author(s) -
M.M. das Neves,
S.M. Moraes,
V.P. Lanzoni
Publication year - 2000
Publication title -
revista da associação médica brasileira
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.319
H-Index - 37
eISSN - 1806-9282
pISSN - 0104-4230
DOI - 10.1590/s0104-42302000000100004
Subject(s) - medicine , insulin , endocrinology , asymptomatic , diabetes mellitus , chronic alcoholic , cirrhosis , glycemic , stimulus (psychology) , c peptide , pancreas , psychology , psychotherapist
The chronic pancreatitis (CP) may evolve with low insulin levels and develop clinical picture of diabetes mellitus. Low seric levels of insulin and C peptide after stimulus has also been described in asymptomatic alcoholics even with normal glycemic curves. It is known that the chronic alcoholism is the main etiological factor of CP and hepatic diseases, and that the insulin produced by the pancreas is metabolized mainly by the liver. High levels of periferic insulin are described in hepatic cirrhosis due to decrease of hepatic metabolization alone or associated to increase of periferic resistance.