Open AccessO uso da toxina botulínica no tratamento da distonia laríngea (disfonia espasmódica): estudo preliminar com doze pacientes
Author(s) -
Hélio A.G. Teive,
Rosana Hermínia Scola,
Lineu César Werneck,
Aníbal de Quadros,
Emerson L. Gasparetto,
Daniel S. Sá,
Ivar Viana Brandi,
Evaldo Dacheux Macedo Filho
Publication year - 2001
Publication title -
arquivos de neuro-psiquiatria
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 48
eISSN - 1678-4227
pISSN - 0004-282X
DOI - 10.1590/s0004-282x2001000100020
Subject(s) - botulinum toxin , medicine , spasmodic dysphonia , dystonia , blepharospasm , focal dystonia , botulism , anesthesia , surgery , dermatology , psychiatry , biology , genetics
Laryngeal dystonia (spasmodic dysphonia) is a movement disorder characterized by involuntary contractions of laryngeal muscles involved with vocalization. The introduction of botulinum toxin in the treatment of laryngeal dystonia had a major clinical impact due to the striking improvement of symptoms. We report the preliminary results of therapeutical use of botulinum toxin in the treatment of twelve patients with laryngeal dystonia. After an extensive clinical evaluation, the patients underwent a videostroboscopic exam for diagnostic confirmation. Botulinum toxin was injected in the cricothyreoid membrane, directed towards the thyreoaritenoid muscle, with the aid of eletromyography needles. Most of patients who underwent botulinum toxin injection had a significant improvement of their symptoms (83%), with effects lasting for four months in average and without important side effects.