Open AccessAntioxidants Used in Pet Feed
Author(s) -
Florina Bunghez,
Carmen Socaciu,
Giorgiana M. Cătunescu
Publication year - 2012
Publication title -
bulletin of university of agricultural sciences and veterinary medicine cluj-napoca. agriculture
Language(s) - English
Resource type - Journals
eISSN - 1843-5386
pISSN - 1843-5246
DOI - 10.15835/buasvmcn-agr:8801
Subject(s) - genotoxicity , chemistry , food science , toxicology , carcinogen , toxicity , reference dose , animal feed , biology , biochemistry , risk assessment , organic chemistry , computer security , computer science
The aim of this study is to present a documentation about the antioxidants used in pet feed, and the toxicity exerted on pets. Natural and artificial antioxidants are used in the industry of pet feed to protect oils and fats against lipid peroxidation or oxidative rancidity. In the present paper 4 brands of moist and dry feed were analysed. In order to determine the toxicity of the antioxidants used in pet feed, some literature studies regarding genotoxicity, teratogenicity, carcinogenity, allergen potential and fetotoxicity were consulted. After revising the literature we found that: ADI for BHA was established 100 mg/kg bw/day. The NOAEL for a 90 days study was 62,5 mg/kg bw; In a long therm study the NOAEL was 250 mg/kg bw; at reproductive and developmental levels the NOAEL was 0.125 mg/ kg bw and at teratogenic level the NOAEL was 400 mg/kg bw. LD was 2000 mg/kg bw. Following the studies results we can conclude that: TBHQ (BHA secondary metabolite) has 50 carcinogenic effect; TBHQ has genotoxic effect; BHA has no teratogenic effect; BHA has allergen potential.