Open AccessReverse remodeling against the background of cardiac contractility modulation therapy in patients with heart failure and atrial fibrillation
Author(s) -
А. А. Сафиуллина,
Т. М. Ускач,
S.V. Dobrovolskaya,
M. A. Saidova,
М. И. Макеев,
S. N. Tereshchenko
Publication year - 2021
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2022-2948
Subject(s) - ejection fraction , cardiology , medicine , heart failure , atrial fibrillation , contractility , ventricular remodeling , stroke volume
Aim . To study myocardial remodeling in patients with heart failure (HF) with reduced ejection fraction (HFrEF) and atrial fibrillation (AF) against the background of cardiac contractility modulation (CCM) therapy. Material and methods . In a group of 100 patients with HFrEF and AF, transthoracic echocardiography was performed before CCM device implantation and after 2, 6 and 12 months. All patients received longterm optimal medical therapy for HF before surgery. Results . Against the background of CCM therapy, there was a significant increase in left ventricular (LV) ejection fraction, a decrease in LV volume and linear dimensions, a decrease in left atrial volume in patients with coronary and non-coronary HFrEF, with an initial LVEF 35%, and also regardless of AF type. Conclusion . CCM therapy in patients with HFrEF and AF led to favorable myocardial remodeling changes. Further study of CCM effect on echocardiographic parameters in randomized clinical trials is needed.