Open AccessLipid-lowering therapy in outpatients of different ages with coronary artery disease
Author(s) -
С. К. Зырянов,
С. Б. Фитилев,
А. В. Возжаев,
И. И. Шкребнева,
Nikolay N. Landyshev,
Я. Г. Воронько,
А. М. Луценко
Publication year - 2020
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2020-2654
Subject(s) - medicine , medical prescription , coronary artery disease , atorvastatin , rosuvastatin , simvastatin , gastroenterology , pharmacology
Aim. To conduct a pharmacoepidemiologic analysis of lipid-lowering therapy (LLT) in outpatients of different ages with coronary artery disease (CAD). Material and methods . A total of 805 medical records of outpatients with CAD were analyzed in this pharmacoepidemiologic, cross-sectional study conducted at primary care facility of Moscow. The total sample of patients was divided into 3 age groups: group 1 — 0,05). Dual LLT was prescribed rarely (4,9%, 3,9%, 0,9%, respectively), especially in patients ≥75 years (p 0,05); patients ≥75 received rosuvastatin less often (p 0,05), as well as the proportion of patients not achieved target LDL-C 0,05). Conclusion. The study demonstrated no significant influence of patient age on LLT prescription rates, LDL-C control, and prevalence of irrational drug combinations in outpatients with CAD. Rates of dual LLT, structure and intensity of statin therapies differed depending on age groups.