Open AccessConventional risk factors and arterial bed parameters in patients with coronary artery disease younger and older than 50 years
Author(s) -
A. Khromova,
Л. И. Салямова,
Olga Kvasova,
В. Э. Олейников
Publication year - 2020
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2020-2541
Subject(s) - medicine , cardiology , coronary artery disease , arterial stiffness , coronary arteries , family history , aorta , disease , common carotid artery , intima media thickness , artery , carotid arteries , blood pressure
Aim . To study conventional risk factors and arterial stiffness parameters to identify non-invasive markers of coronary atherosclerosis in patients with and without history of cardiovascular disease, with premature and physiological vascular aging. M aterialand methods. The study included 198 patients with coronary artery disease (CAD) and 57 healthy people. The subjects were divided into two cohorts: younger and older than 50 years. Each group included patients with newly diagnosed acute coronary syndrome with/without history of cardiovascular disease (CAD and/or hypertension). Conventional risk factors were analyzed in all subjects. Ultrasound radiofrequency of common carotid arteries (CCA), applanation tonometry, volume sphygmography were performed. R e sults . Analysis of arterial parameters in individuals 50 years of age, AUC for the IMT was 0,948, threshold — 607,5 (p=0,000); for the beta stiffness index — 0,740, threshold — 8,84 (p=0,000); for L-/CAVI 1 — 0,861, threshold — 8,4 (p=0,000). Conclusion . Timely identification of atherosclerotic markers using noninvasive techniques can improve the prediction of cardiovascular events. A comprehensive non-invasive examination of the arteries with determination of IMT, beta stiffness index, and L-/CAVI 1 will probably identify young people with an unfavorable absolute cardiovascular risk. .