Open AccessVitamin D role in arterial hypertension development
Author(s) -
Е. Н. Дудинская,
О. Н. Ткачева
Publication year - 2012
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2012-3-77-81
Subject(s) - vitamin d and neurology , endocrine system , medicine , pathophysiology of hypertension , blood pressure , endocrinology , renin–angiotensin system , vitamin d deficiency , endothelial dysfunction , vitamin , aldosterone , hormone
Recently obtained data have identified potential mechanisms linking D-endocrine system and blood pressure regulation. Vitamin D deficiency is associated with calcium metabolism disregulation, increased tonus of renin-angiotensin-aldosterone system, endothelial dysfunction, and metabolic syndrome development. The evidence presented suggests a possibility for developing a new, vitamin D-derived class of antihypertensive medications. This review discusses the mechanisms of arterial hypertension development which are related to vitamin D metabolism in humans.