Open AccessHeart rate reduction as a therapeutic goal: focus on primary prevention
Author(s) -
Yulia Orlova,
G. V. Makarova,
Г. В. Михайлова,
Ф Т Агеев
Publication year - 2012
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2012-1-89-95
Subject(s) - medicine , overweight , myocardial infarction , cardiology , heart failure , primary prevention , coronary artery disease , disease , risk factor , secondary prevention , coronary heart disease , intensive care medicine , obesity
Recently published studies have demonstrated a direct link between heart rate (HR) and prognosis across various populations and clinical groups, including elderly people, patients with arterial hypertension, myocardial infarction, and coronary artery stenting, overweight patients, or even young people with relatively low cardiovascular risk levels. HR is considered as an additional independent risk factor (RF) of cardiovascular disease (CVD). However, thus far, pharmaceutical HR reduction has been demonstrated to improve prognosis only in patients with coronary heart disease or chronic heart failure. The results in CVD-free patients have been contradictory. The review discusses the potential of different HR-reducing therapeutic regimens, as a part of primary CVD prevention.