Open AccessOrgano-protective effects of quinapril: pharmacogenetic aspects
Author(s) -
D.A. Sychev Sychev,
О. В. Муслимова
Publication year - 2011
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2011-2-98-101
Subject(s) - quinapril , medicine , pharmacogenetics , polymorphism (computer science) , pharmacology , gene , genetics , genotype , ace inhibitor , angiotensin converting enzyme , biology , blood pressure
The review presents current experimental and clinical evidence on organo-protective effects of an ACE inhibitor quinapril. These effects are dependent on I/D polymorphism of ACE gene. The data available are consistent that quinapril could modulate this genetic risk factor, highly prevalent in Russian patients.