Open AccessGlycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
Author(s) -
М. А. Коротина,
И. Г. Починка,
А. А. Фролов,
Светлана Николаевна Ботова,
Л Г Стронгин
Publication year - 2021
Publication title -
rossijskij kardiologičeskij žurnal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.141
H-Index - 14
eISSN - 2618-7620
pISSN - 1560-4071
DOI - 10.15829/1560-4071-2021-4239
Subject(s) - medicine , glycemic , myocardial infarction , diabetes mellitus , type 2 diabetes , concomitant , insulin , cardiology , endocrinology
Aim . To investigate the relationship between abnormal glycemia levels during inpatient treatment for acute myocardial infarction (AMI) in patients with type 2 diabetes (T2D) and long-term prognosis. Material and methods . The single-center cohort study included patients with AMI and concomitant T2D who were hospitalized consecutively for 200 days. A total of 237 patients were included. The median number of blood glucose measurements during hospitalization was 15 [8; 20] times. Long-term outcome was estimated at 365 days after hospitalization. Results . The first glycemic value on admission was 13,6±5,9, while the average glycemia during hospitalization was 10,0±3,5 mmol/L. Within 12 follow-up period, 53 deaths were recorded. It was found that exceeding the glycemic threshold of 10,0 mmol/L in more than 45% of measurements during hospitalization was associated with a 3-fold increase in the risk of an unfavorable outcome within 12 months. Predictors of poor glycemic control are insulin therapy before MI and blood glucose at admission >12,1 mmol/L. Conclusion . Poor glycemic control (>45% of glucose measurements above the threshold of 10,0 mmol/L) during hospitalization for AMI in patients with T2D is associated with an increased risk of in-hospital death and during the next 12 months, including in patients who underwent endovascular treatment.