Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol | Zendy

L. A. Yakovishin | Zendy; V. I. Grishkovets | Zendy; Е Н Корж | Zendy; I. Golovchenko | Zendy; A. A. Nagirnyak | Zendy

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Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol

Author(s) -

L. A. Yakovishin,

V. I. Grishkovets,

Е Н Корж,

I. Golovchenko,

A. A. Nagirnyak

Publication year - 2020

Publication title -

chimica techno acta

Language(s) - English

Resource type - Journals

eISSN - 2411-1414

pISSN - 2409-5613

DOI - 10.15826/chimtech.2020.7.4.02

Subject(s) - isopropyl alcohol , chemistry , triterpene , aqueous solution , isopropyl , hydrogen bond , alcohol , fourier transform infrared spectroscopy , hydrophobic effect , molecule , glycoside , organic chemistry , medicine , physics , alternative medicine , pathology , quantum mechanics

The 1:1 molecular complex of ivy triterpene glycoside hederasaponin C (HedC) with cholesterol (Chol) was obtained in aqueous isopropyl alcohol. The stability constant of (3.3 ± 0.7)∙106 (mol/L)–1 was calculated for the complex. The complexation was studied by UV- and ATR IR-Fourier spectroscopy, and method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex.

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