Open AccessMolecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
Author(s) -
L. A. Yakovishin,
В. И. Гришковец,
Е Н Корж,
I. Golovchenko,
A. A. Nagirnyak
Publication year - 2020
Publication title -
chimica techno acta
Language(s) - English
Resource type - Journals
eISSN - 2411-1414
pISSN - 2409-5613
DOI - 10.15826/chimtech.2020.7.4.02
Subject(s) - isopropyl alcohol , chemistry , triterpene , aqueous solution , isopropyl , hydrogen bond , alcohol , fourier transform infrared spectroscopy , hydrophobic effect , molecule , glycoside , organic chemistry , medicine , physics , alternative medicine , pathology , quantum mechanics
The 1:1 molecular complex of ivy triterpene glycoside hederasaponin C (HedC) with cholesterol (Chol) was obtained in aqueous isopropyl alcohol. The stability constant of (3.3 ± 0.7)∙106 (mol/L)–1 was calculated for the complex. The complexation was studied by UV- and ATR IR-Fourier spectroscopy, and method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex.