
Kidney transplantation and bone disease: risk factors of development and diagnostics
Author(s) -
Н. Ветчинникова
Publication year - 2017
Publication title -
vestnik transplantologii i iskusstvennyh organov
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.137
H-Index - 5
eISSN - 2412-6160
pISSN - 1995-1191
DOI - 10.15825/1995-1191-2017-1-111-121
Subject(s) - medicine , osteoporosis , fibroblast growth factor 23 , transplantation , bone disease , bone remodeling , kidney transplantation , kidney disease , disease , vitamin d and neurology , risk factor , parathyroid hormone , intensive care medicine , calcium
Bone disease is a serious and common condition in patients after kidney transplantation. The review analyzed the causes of bone disorders in the early and late postoperative period that are associated with renal transplantation: fibroblast growth factor 23, parathyroid hormone, vitamin D, immunosuppressive therapy and imbalance of mineral metabolism. It shows the most common clinical variant of the post-transplant bone disease – secondary osteoporosis, risk factors of its development and complications. It presents the diagnostic algorithm for dynamic monitoring and evaluating the effectiveness of the treatment of bone disorders