Open AccessTHE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
Author(s) -
V Logvinenko,
Л. Ракитина,
Г Н Пономаренко,
В. П. Костюченко,
С. С. Саркисян,
В. А. Бердникова
Publication year - 2014
Publication title -
infekciâ i immunitet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.137
H-Index - 5
eISSN - 2313-7398
pISSN - 2220-7619
DOI - 10.15789/2220-7619-2013-3-275-278
Subject(s) - brucellosis , immunology , cytotoxic t cell , immunodeficiency , disease , antibody , medicine , immunity , humoral immunity , immune system , cellular immunity , biology , in vitro , biochemistry
. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.