Open AccessTHE INTERDEPENDENCE OF THE CYTOKINE STATUS AND THE SEVERITY OF INTOXICATION SYNDROME IN INFLUENZA
Author(s) -
Любовь Васильевна Волощук,
Е Г Головачева,
А. Л. Мушкатина,
Л В Осидак,
П. В. Заришнюк,
Andrew Go
Publication year - 2014
Publication title -
infekciâ i immunitet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.137
H-Index - 5
eISSN - 2313-7398
pISSN - 2220-7619
DOI - 10.15789/2220-7619-2013-3-263-268
Subject(s) - medicine , cytokine , disease , immunology , tumor necrosis factor alpha
. The goal of study was to evaluate cytokines level in blood of 60 patients with uncomplicated influenza and its relations with severity of intoxication symptoms. High level of TNFα, IL-10, IL-1Rа and low level of IFNγ was measured in serum of patients with severe intoxication syndrome during acute phase of disease. The duration of intoxication syndrome of influenza had a direct correlation with the concentration of TNFα, IL-6, IL-8, IL-1Rа, IL-10 and the opposite of IL-1β.