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Laboratory Efficacy of Amoxicillin for the Control of Streptococcus iniae Infection in Sunshine Bass
Author(s) -
Darwish Ahmed M.,
Ismaiel Adnan A.
Publication year - 2003
Publication title -
journal of aquatic animal health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 52
eISSN - 1548-8667
pISSN - 0899-7659
DOI - 10.1577/h03-016
Subject(s) - streptococcus iniae , biology , amoxicillin , morone , bass (fish) , veterinary medicine , streptococcus , mediastinitis , microbiology and biotechnology , fish <actinopterygii> , fishery , antibiotics , bacteria , medicine , surgery , genetics
Abstract An experimental trial was performed to evaluate the efficacy of amoxicillin in controlling Streptococcus iniae infection in sunshine bass (a hybrid of female white bass Morone chrysops × male striped bass M. saxatilis ). Minimum‐inhibitory‐concentration studies of amoxicillin against multiple S. iniae isolates showed a sensitivity range of 0.0156–0.5 μg/mL. The amoxicillin dose levels tested were 30, 50, 80, and 120 mg of active ingredient per kilogram of fish body weight per day. Administration of medicated feed started 1 d after infection by immersion exposure to S. iniae and continued for eight consecutive days; this was followed by an observation at 15 d posttreatment. Amoxicillin increased the survival rate from 1% in the infected, nonmedicated group to an average of 95% in the infected groups receiving the four doses; there were no significant differences among the medicated groups. Survivors of the infection were not found to be carriers of the bacteria (i.e., there was negative bacterial isolation).