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Quantitative Scoring of Gill Pathology of Walleyes Exposed to Hydrogen Peroxide
Author(s) -
Tort M. J.,
Pasnik D. J.,
FernandezCobas C.,
Wooster G. A.,
Bowser P. R.
Publication year - 2002
Publication title -
journal of aquatic animal health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 52
eISSN - 1548-8667
pISSN - 0899-7659
DOI - 10.1577/1548-8667(2002)014<0154:qsogpo>2.0.co;2
Subject(s) - stizostedion , hydrogen peroxide , gill , biology , fish <actinopterygii> , toxicity , necrosis , pathology , zoology , toxicology , fishery , medicine , biochemistry
Hydrogen peroxide is currently being evaluated as a potential chemotherapeutant for a variety of external disease organisms of fish. Research in our laboratory has focused on delineating effective hydrogen peroxide dosing regimes for treating bacterial gill disease in walleyes Stizostedion vitreum . Results from target animal safety studies indicate that walleyes are particularly sensitive to hydrogen peroxide. Acute toxicity is evident from histopathologic inspection of gills (which show extensive epithelial lifting and necrosis) of fish treated with high doses of hydrogen peroxide. A digitized scoring method was used to quantify the severity of the gill lesions in juvenile walleyes exposed to hydrogen peroxide.