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Communications: Metastatic Gill Lesions Secondary to Cardiac Hemangioendotheliosarcomas in the Teleost Fish Mangrove Rivulus
Author(s) -
Couch John A.
Publication year - 1996
Publication title -
journal of aquatic animal health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 52
eISSN - 1548-8667
pISSN - 0899-7659
DOI - 10.1577/1548-8667(1996)008<0325:cmglst>2.3.co;2
Subject(s) - biology , pathology , gill , anatomy , cytoplasm , endothelium , fish <actinopterygii> , microbiology and biotechnology , endocrinology , fishery , medicine
Gill neoplasms have been infrequently described for teleost fishes. Nine of 51 cases of primary cardiac endothelial cell neoplasms of a teleost fish species, mangrove rivulus Rivulus marmoratus , also possessed endothelial cell neoplasms in their gills. These neoplasms occurred in the afferent arterioles of the gill filaments. They were made up of round cells or spindle cells that had nuclei similar to typical endothelial cell nuclei. The large gill neoplasms, with more anaplastic cells, penetrated the walls of the gill arterioles and invaded adjacent gill tissues. Supporting evidence for the metastatic nature of these gill neoplasms includes the following: (1) they were secondary in timing, numbers, and size to the advanced sarcomas of the heart; (2) cell phenotypes of both gill and cardiac neoplasms were similar in cytoplasmic and nuclear features; (3) the cardiac neoplasms appeared to be shedding neoplastic endothelial cells into the lumen of the bulbus arteriosus with a direct route via the circulation of the ventral aorta to the afferent arterioles of the gills; and (4) direct evidence that the gill neoplasms arose from gill endothelium was lacking.