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Oxytetracycline Residue in Striped Bass Muscle
Author(s) -
Xu Dehai,
Rogers Wilmer A.
Publication year - 1994
Publication title -
journal of aquatic animal health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 52
eISSN - 1548-8667
pISSN - 0899-7659
DOI - 10.1577/1548-8667(1994)006<0349:orisbm>2.3.co;2
Subject(s) - oxytetracycline , bass (fish) , morone saxatilis , biology , zoology , intraperitoneal injection , detection limit , maximum residue limit , fish <actinopterygii> , anatomy , medicine , fishery , endocrinology , chemistry , chromatography , biochemistry , antibiotics , ecology , pesticide residue , pesticide
Tissue residues were measured in striped bass Morone saxatilis that had been injected intraperitoneally with 50 mg oxytetracycline (OTC)/kg or had been fed a ration containing 75 mg OTC/kg of fish daily for 10 d. Concentration of OTC in muscle of fish fed medicated feed was below the quantitation limit in 67% of the fish 12 d after treatment and was below the quantitation limit in all fish after 16 d at 23°C. The calculated terminal elimination rate constant (β) was 0.20/d (range, 0.15–0.37/d), and the half‐life was 2.7 d (range, 1.9–4.5 d). The concentration of OTC in muscle after intraperitoneal injection was below the quantitation limit after 24 d at 23°C. The β‐value was 0.34/d and half‐life was 2.0 d in fish injected with OTC intraperitoneally.