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Potential Use of Vaccines Based on Cell‐Wall‐Defective or ‐Deficient (L‐form) Aeromonas salmonicida for the Control of Furunculosis
Author(s) -
McIntosh D.,
Austin B.
Publication year - 1993
Publication title -
journal of aquatic animal health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 52
eISSN - 1548-8667
pISSN - 0899-7659
DOI - 10.1577/1548-8667(1993)005<0254:puovbo>2.3.co;2
Subject(s) - aeromonas salmonicida , salmo , biology , rainbow trout , microbiology and biotechnology , virulence , limiting , aeromonas , virology , fish <actinopterygii> , fishery , bacteria , gene , genetics , mechanical engineering , engineering
In laboratory‐based experiments with Atlantic salmon Salmo salar and rainbow trout Oncorhynchus mykiss , the efficacy of vaccines composed of forms of Aeromonas salmonicida that have defective or deficient cell walls (L‐forms) was compared with the efficacy of vaccines of formalin‐inactivated whole cells grown in standard or in iron‐limiting conditions. LysozymeEDTA‐induced L‐form preparations conferred more protection than did inactivated whole cells or benzylpenicillin‐induced L‐forms after challenge with two virulent cultures of A. salmonicida