Premium
Extracellular Products and Endotoxin from Aeromonas hydrophila: Effects on Age‐0 Channel Catfish
Author(s) -
Thune R. L.,
Graham T. E.,
Riddle L. M.,
Amborski R. L.
Publication year - 1982
Publication title -
transactions of the american fisheries society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 86
eISSN - 1548-8659
pISSN - 0002-8487
DOI - 10.1577/1548-8659(1982)111<404:epaefa>2.0.co;2
Subject(s) - ictalurus , catfish , aeromonas hydrophila , aeromonas , biology , intraperitoneal injection , fish <actinopterygii> , microbiology and biotechnology , ed50 , extracellular , toxicology , ictaluridae , bacteria , fishery , pharmacology , biochemistry , genetics , in vitro
The effects of the extracellular products (ECP) and endotoxin from Aeromonas hydrophila grown in a defined medium were determined following intraperitoneal injection of young‐of‐the‐year channel catfish Ictalurus punctatus. Endotoxin had no lethal effects in doses as high as 400 μg per 7.2‐g fish, whereas ECP had a 48‐hour median lethal concentration (LD50) of 15.7 μg per 7.2‐g fish. Sublethal doses of ECP often produced many of the gross pathologies associated with A. hydrophila infections. The primary lethal factor was heat‐labile at 56 C for 10 minutes, but a heat‐stable component was also implicated.