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Toxicology Studies of Antimycin, a Fish Eradicant
Author(s) -
Herr F.,
Greselin E.,
Chappel C.
Publication year - 1967
Publication title -
transactions of the american fisheries society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 86
eISSN - 1548-8659
pISSN - 0002-8487
DOI - 10.1577/1548-8659(1967)96[320:tsoaaf]2.0.co;2
Subject(s) - toxicity , acute toxicity , antimycin a , fish <actinopterygii> , toxicology , respiration , chemistry , intraperitoneal injection , biology , pharmacology , biochemistry , anatomy , fishery , mitochondrion , organic chemistry
Antimycin (Fintrol R ) is used as an eradicant for coarse fish. Its usefulness for this purpose is based on its extremely high immersion toxicity for fish. Observations made of the acute toxicity of Antimycin for goldfish by immersion, intraperitoneal or oral injection suggest an effect on respiration at the gills. Acute and chronic toxicity studies indicate that Antimycin has relatively low toxicity for mammals which is another prerequisite of its usefulness as a fishery tool. There is a moderate irritation potential if the compound is applied repeatedly in high concentration to the skin or eye of rabbits. The degradation products of Antimycin were found to be devoid of toxicity. In view of the high specificity of this agent for fish, the rapidity with which it breaks down and the safety of the degradation products, Antimycin would appear to have marked advantages over fish eradicants currently in use.