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Response of Brook, Rainbow, and Brown Trout to Various Dosages of Sulfamerazine
Author(s) -
Gutsell James S.,
Snieszko S. F.
Publication year - 1949
Publication title -
transactions of the american fisheries society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 86
eISSN - 1548-8659
pISSN - 0002-8487
DOI - 10.1577/1548-8659(1947)77[93:robrab]2.0.co;2
Subject(s) - sulfamerazine , rainbow trout , dose , brown trout , fishery , zoology , ecology , biology , fish <actinopterygii> , trout , microbiology and biotechnology , sulfadiazine , pharmacology , antibiotics
During experiments in 1945 and 1946 in which sulfamerazine in the food was found to be effective in the treatment of furunculosis in brook trout (Salvelinus fontinalis), it was observed that fish grew faster on untreated food and that when the dosage rate was heavy they did not eat all the food and showed a dislike for it. To determine the effect of sulfamerazine treatment on growth and to learn whether the drug injures various trout species, brook trout and rainbow trout (Salmo gairdnerii) were tested in 1946 and brown trout (Salmo trutta) in 1947. The daily dosage rates chosen were 0, 5, 10, and 15 grams of the drug per 100 pounds of fish (0, 11, 22, 33 grams per 100 kilograms). It was observed from this experiment that: (1) sulfamerazine was not lethal; (2) the drug had no apparent injurious effect; (3) retardation of growth was caused by reduced consumption of food containing the drug; (4) there was great variation among the three species of trout in their response to sulfamerazine, e.g., the growth of rainbow trout was not affected, growth of brook trout was reduced by heavier dosage rates, and growth of brown trout was stopped by 5‐gram or greater dosage rates; (5) hemoglobin and number of erythrocytes increased in brown trout treated with sulfamerazine in the food; (6) a very small dosage, begun in time, appears to be sufficient to control furunculosis in brown trout.