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The ethics of preimplantation genetic diagnosis
Author(s) -
ElToukhy Tarek,
Williams Clare,
Braude Peter
Publication year - 2008
Publication title -
the obstetrician and gynaecologist
Language(s) - English
Resource type - Journals
eISSN - 1744-4667
pISSN - 1467-2561
DOI - 10.1576/toag.10.1.049.27378
Subject(s) - preimplantation genetic diagnosis , sex selection , ethical issues , gynecology , genetic testing , disease , medicine , prenatal diagnosis , psychology , pregnancy , obstetrics , genetics , biology , engineering ethics , fetus , pathology , engineering
Key content• Preimplantation genetic diagnosis (PGD) is an alternative to prenatal diagnosis and termination of affected pregnancies. • PGD for late‐onset and susceptibility conditions requires careful consideration on a case‐by‐case basis. • PGD for sex selection for nonmedical reasons is prohibited in the UK. • The use of PGD is expanding and its ethical implications are likely to increase.Learning objectives• To recognise the main ethical difficulties raised by the practice of PGD. • To understand the role of regulation. • To appreciate the potential ethical implications of new developments in reproductive genetics.Ethical issues• Is PGD more acceptable than prenatal diagnosis and termination for all disorders? • Should PGD be offered for Huntington disease on a nondisclosure basis? • Should noncarrier embryos be replaced in preference to carrier embryos in recessive conditions? • Is PGD for HLA typing a step too far?Please cite this article as: El‐Toukhy T, Williams C, Braude P. The ethics of preimplantation genetic diagnosis. The Obstetrician & Gynaecologist 2008;10:49–54.