Open AccessFormula Alternatives for Nutrition Therapy of Children with Cow’s Milk Protein Allergy
Author(s) -
Г. А. Новик,
М. В. Жданова,
Ю. О. Зайцева,
Anastasia Demidova
Publication year - 2021
Publication title -
voprosy sovremennoj pediatrii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.12
H-Index - 5
eISSN - 1682-5535
pISSN - 1682-5527
DOI - 10.15690/vsp.v20i3/2272
Subject(s) - allergy , medicine , infant formula , milk protein , food allergy , food protein , cow milk , milk allergy , therapeutic approach , placebo , clinical trial , pediatrics , disease , immunology , food science , pathology , chemistry , alternative medicine
Well-recognized tactic for the management of formula-fed children with cow’s milk protein allergy (CMPA) is exclusion of whole cow milk protein and its replacement with extensively hydrolyzed or amino acid formula. One of the most topical issue is the choice of therapeutic formula for a child with CMPA. This article presents information about the clinical manifestations of CMPA and describes the principles of nutrition therapy. All the stages of preparation of adapted therapeutic formula are discussed in detail. It has been shown that the choice of therapeutic formula for a child with CMPA depends on the disease clinical manifestations, their severity, and the presence of comorbid conditions. Current requirements for extensively hydrolyzed formula are reduced to limitations in the size of peptides with immunoreactive properties and indicate the need for evidence of the clinical efficacy of such formula in double-blind placebo-controlled studies.