Open AccessHuman embryo genome editing: an interdisciplinary approach
Author(s) -
Elena Grebenshchikova,
Гребенщикова Елена Георгиевна,
Denis Andreyuk,
Андреюк Денис Сергеевич,
Pavel Volchkov,
Волчков Павел Юрьевич,
М. А. Воронцова,
Воронцова Мария Владимировна,
Е. К. Гинтер,
Гинтер Евгений Константинович,
В. Л. Ижевская,
Ижевская Вера Леонидовна,
Alexey Lagunin,
Лагунин Алексей Александрович,
A. V. Polyakov,
Поляков Александр Владимирович,
Olga V. Popova,
Попова Ольга Владимировна,
Svetlana Smirnikhina,
Смирнихина Светлана Анатольевна,
P. Ya. Tishchenko,
Тищенко Павел Дмитриевич,
Trofimov D.Yu. Trofimov,
Трофимов Дмитрий Юрьевич,
Sergey I. Kutsev,
Куцев Сергей Иванович
Publication year - 2021
Publication title -
vestnik rossijskoj akademii medicinskih nauk
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 15
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn1269
Subject(s) - bioethics , conceptualization , genome editing , human genome , engineering ethics , human genetics , genome , biology , computer science , genetics , engineering , gene , artificial intelligence
The prospects for the human embryos genome editing cause intense debates both in the scientific community and in general public. While the main attention of scientists is focused on the safety, effectiveness and clinical feasibility of the inherited genome editing, the public pays attention to the bioethical aspects of the issue - the prospects of a baby design, the development of new forms of social inequality and intervention in human evolution. The authors conducted an interdisciplinary analysis of medical genetics and bioethical issues of human embryo genome editing, revealed the possibilities and limitations of genome editing technology, and considered the specifics of ethical discussions. The conceptualization of the main approaches of natural and social sciences in a general theoretical framework made it possible not only to take into account the complex nature of the issues, but also to create the prerequisites for its further productive discussion.