Open AccessDiabetes Mellitus and Thyroid Dysfunction, Including Autoimmune Genesis. Mutual Influence of Pathologies
Author(s) -
A. V. Tkachuk,
A. V. Tkachuk,
Margarita S. Mikhina,
Margarita S. Mikhina,
Людмила Ибрагимовна Ибрагимова,
Людмила Ибрагимовна Ибрагимова,
Tatiana Vasil'evikonova,
Tatiana Vasil'evikonova,
Е. А. Трошина,
Е. А. Трошина
Publication year - 2020
Publication title -
vestnik rossijskoj akademii medicinskih nauk
Language(s) - English
Resource type - Journals
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn1182
Subject(s) - thyroid , medicine , diabetes mellitus , endocrine system , hormone , microangiopathy , endocrinology , disease , homeostasis , glucose homeostasis , insulin resistance
Thyroid disease, including autoimmune genesis, and diabetes mellitus are the two most common endocrine diseases in clinical practice. These pathologies have a mutual influence on each other. On the one hand, thyroid hormones are involved in regulation of carbohydrate metabolism: excessive production of thyroid hormones is associated with hyperglycemia, while hypothyroidism has a decreased level of glucose production by the liver. On the other hand, glucose homeostasis disorder affects the functional state of the thyroid gland: dystrophic, sclerotic and atrophic processes are developing in thyroid gland, what is a manifestation of diabetic microangiopathy. This article demonstrates the need to take into account the mutual influence of pathologies for optimal treatment of this conditions.