Open AccessEndothelial Dysfunction Indicators in Patients with Diabetic Foot Syndrome
Author(s) -
Petr A. Gerasimchuk,
П. В. Кісіль,
Vadim Vlasenko,
A V Pavlyshin
Publication year - 2014
Publication title -
vestnik rossijskoj akademii medicinskih nauk
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 15
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn.v69i5-6.1053
Subject(s) - medicine , microcirculation , endothelial dysfunction , hemodynamics , reactive hyperemia , diabetes mellitus , endothelium , laser doppler velocimetry , pathogenesis , cardiology , nitric oxide , diabetic foot , vasodilation , blood flow , endocrinology
In recent years, scientists have become increasingly interested in the role of the endothelium in the pathogenesis of vascular lesions of various origins, including diabetic patients. Therefore, the aim of the study was to investigate the expression of endothelial dysfunction in patients with diabetic foot syndrome (DFS), by examining the levels of nitric oxide, endothelin-1 levels in the serum, as well as lower limb microcirculation by laser doppler flowmetry.