Open AccessRESULTS AND PROSPECTS OF INTERFERONE INDUCERS USING IN INFECTIOUS DISEASES TREATMENT
Author(s) -
Ф. И. Ершов,
А. А. Шульдяков,
М. Г. Романцов,
Е. П. Ляпина,
Л. А. Соболева
Publication year - 2013
Publication title -
vestnik rossijskoj akademii medicinskih nauk
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 15
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn.v68i10.788
Subject(s) - viremia , interferon , medicine , immunology , chronic hepatitis , brucellosis , tuberculosis , inducer , endogeny , virology , pharmacology , human immunodeficiency virus (hiv) , biology , virus , biochemistry , pathology , gene
There is represented the current classification of interferon inducers of various chemical groups related to antiviral agents, described the mechanisms of synthesis of different types of endogenous interferon in blood serum. The effectiveness of methylglucamine acridonacetates in integrated treatment of chronic hepatitis C, tuberculosis with HIV infection background, chronic brucellosis, arboviral diseases, including West Nile fever , as well as influenza and acute respiratory infections are shown. For successful treatment of acute and chronic diseases with endogenous interferon inducers should be applied as early as possible, at an average level of viremia , to enhance the effect of drugs with the directed etiotropic action and immunomodulators , which achieves the optimal pharmacotherapeutic effect.