CLINICAL SIGNIFICANCE OF INSULIN RESISTANCE SYNDROME IN DEVELOPMENT OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PRIMARY GOUT | Zendy

N. N. Kushnarenko | Zendy; А. В. Говорин | Zendy; О. А. Щербакова | Zendy; С. Г. Сотникова | Zendy; O. V. Ivanitskaya | Zendy

Open Access

CLINICAL SIGNIFICANCE OF INSULIN RESISTANCE SYNDROME IN DEVELOPMENT OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PRIMARY GOUT

Author(s) -

N. N. Kushnarenko,

А. В. Говорин,

О. А. Щербакова,

С. Г. Сотникова,

O. V. Ivanitskaya

Publication year - 2012

Publication title -

annals of the russian academy of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.122

H-Index - 15

eISSN - 2414-3545

pISSN - 0869-6047

DOI - 10.15690/vramn.v67i2.123

Subject(s) - endothelial dysfunction , gout , insulin resistance , medicine , endocrinology , incidence (geometry) , insulin , physics , optics

Endothelial function has been studied in 175 males with primary gout. It has been established that incidence of endothelial dysfunction in patients with primary gout was associated with the clinical course and was marked most of all in patients who had a chronic gout. The correlations found between the parameters of endothelial dysfunction and impaired carbohydrate metabolism suggest close link and coordination between the above processes which contribute greatly to development and progress of atherosclerosis in such patients.

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