Open AccessINFLUENCE OF VARIOUS TYPES OF ANESTHESIA IN ONCOSURGICAL PRACTICE ON IMMUNE PARAMETERS
Author(s) -
Sayat Tanatarov,
М. И. Неймарк,
Р.К. Жакупов
Publication year - 2012
Publication title -
vestnik rossijskoj akademii medicinskih nauk
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 15
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn.v67i12.476
Subject(s) - anesthesia , psychology , mathematics , medicine
The aim of investigation is to reveal dependence of indicators of a phagocytes-macrophageal link and cytokine regulation at the operated patients with malignant new growths from a way of anesthesia. 274 patients with a gastroenteric cancer which was exposed to radical operative interventions with use of various ways of anesthesia (total intravenous, inhalation and intravenous-epidural) are surveyed. Existence of dependence of indicators of a phagocytes link of immunity and cytokine regulation from a way of surgical anesthesia at oncological patients is revealed. Most the imbalance of the studied phagocytes and cytokine mechanisms was shown at total intravenous, in the smallest – at combined intravenous epidural anesthesia that serves one of factors for the recommendation of its priority use in oncosurgical practice.