Open AccessCYTOLOGIC FEATURES ОF BRONCHOALVEOLAR LAVAGE IN EVALUATION OF COURSE OF EXOGENOUS ALLERGIC ALVEOLITIS
Author(s) -
Л. Н. Лепеха,
Екатерина Анатольевна Александрова,
Г. В. Евгущенко,
Natalia Makaryants,
Olga Lovacheva
Publication year - 2012
Publication title -
vestnik rossijskoj akademii medicinskih nauk
Language(s) - English
Resource type - Journals
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn.v67i11.469
Subject(s) - extrinsic allergic alveolitis , bronchoalveolar lavage , immunology , medicine , population , lung , environmental health
Application of complex of modern cytologic methods of research bronchoalveolar lavage allowed to allocate most characteristics of development of lymphocytic and macrophagic reaction of bronchial tree in different course of exogenous allergic alveolitis. The most indicative in assessment of origin of exogenous allergic alveolitis development is the characteristics of macrophagic population. In acute course of exogenous allergic alveolitis the considerable number of young activated and non-activated macrophages, increased number of mature phagocytes is observed. Even more significant increase of phagocytic macrophages is observed at dissemination which is primarily is connected with participation of these cells in lymphocytic apoptosis which takes place in high percentage of lymphocytes (up to 49%). Increased number of mature phagocytes is observed at chronic course of exogenous allergic alveolitis that is an important diagnostic pattern of this option of development of exogenous allergic alveolitis in association with the lowest T-helpers/T-supressors index.