Open AccessModern Approaches to the Management of Children with Atypical Hemolytic Uremic Syndrome
Author(s) -
Х М Эмирова,
Tatiana Abaseeva,
А. А. Баранов,
Nato D. Vashakmadze,
Е.А. Вишнева,
Г. А. Генералова,
Ekaterina Zakharova,
Т. А. Калюжная,
С. И. Куцев,
Leyla Namazova-Baranova,
Т. П. Макарова,
Т. В. Маргиева,
Sofya Mstislavskaya,
Alexandr Muzurov,
Т.Е. Панкратенко,
M.M. Shilova Shilova,
М. В. Федосеенко
Publication year - 2022
Publication title -
pediatričeskaâ farmakologiâ
Language(s) - English
Resource type - Journals
eISSN - 2500-3089
pISSN - 1727-5776
DOI - 10.15690/pf.v19i2.2400
Subject(s) - medicine , atypical hemolytic uremic syndrome , etiology , intensive care medicine , disease , pediatrics , differential diagnosis , immunology , pathology , antibody , complement system
Experts of the Union of Pediatricians of Russia have developed modern guidelines on management of children with atypical hemolytic uremic syndrome (aHUS). aHUS is ultra-rare (orphan) disease with progressive and relapsing course during the life with potentially life-threatening state. This article covers issues of disease etiology, pathogenesis, and classification. Specific attention is paid to the diagnosis, differential diagnosis, and therapy of aHUS according to the evidence-based approaches.