Open AccessThe Jarisch-Herxheimer Reaction in a Child with Community-Acquired Pneumonia: a Clinical Case
Author(s) -
В. К. Таточенко,
М. Д. Бакрадзе,
А. Г. Агаронян
Publication year - 2018
Publication title -
pediatričeskaâ farmakologiâ
Language(s) - English
Resource type - Journals
eISSN - 2500-3089
pISSN - 1727-5776
DOI - 10.15690/pf.v15i3.1906
Subject(s) - bartonellosis , medicine , pneumonia , amoxicillin , prednisolone , doxycycline , sepsis , antibiotics , immunology , microbiology and biotechnology , biology , bartonella henselae , serology , antibody
The Jarisch-Herxheimer reaction (JHR) is a shock-like state in response to antimicrobial therapy due to the release of toxins from decomposing microbial bodies. The reaction mainly occurs in patients with spirochetosis, less often in patients with brucellosis, bartonellosis, rickettsiosis, and can be possibly observed in patients with sepsis or meningococcemia. The JHR in children with community-acquired pneumonia has not been previously described. The article provides the author’s own observation of a similar reaction in a child with upper lobe pneumonia associated with amoxicillin treatment and resolved after the administration of prednisolone.