Open AccessMORPHOFUNCTIONAL FEATURES OF THE PLACENTA OF NEWBORNS IN BIRTH-INDUCED CRITICAL CONDITIONS: THE RESULTS OF A RETROSPECTIVE COHORT STUDY
Author(s) -
О.А. Senkevich,
К. Е. Попова,
О. В. Кожарская,
Денис Мусатов
Publication year - 2017
Publication title -
pediatričeskaâ farmakologiâ
Language(s) - English
Resource type - Journals
eISSN - 2500-3089
pISSN - 1727-5776
DOI - 10.15690/pf.v14i3.1742
Subject(s) - medicine , apgar score , placenta , obstetrics , odds ratio , umbilical cord , birth weight , pregnancy , umbilical artery , fetus , biology , genetics , anatomy
Background. The placenta condition is the health marker of newborns and it can be considered in the early diagnosis of the development of severe pathological conditions in a child. Objective: Our aim was to study the relationship between the placenta characteristics and the risk of a birth-induced critical condition in a child and the risk of having children with the APGAR score of 4 points) were singled out. In multivariate analysis, it was established that the appearance of a birth-induced critical condition with the APGAR score < 4 points was associated with pathological attachment of the umbilical cord (odds ratio, OR, 2.8, 95% confidence interval, CI, 1.1–7.0), placenta weight (OR 5.4, 95% CI 1.9–14.9), signs of chronic fetoplacental insufficiency (OR 7.3, 95% CI 2.9–18.8), impaired blood circulation in the placenta (OR 13.7, 95% CI 4.7–39.3), placental hypoplasia (OR 8.9, 95% CI 2.4–32.4), fetal-placental ratio (OR 8.9, 95% CI 2.4–32.4) as well as low birth weight of a newborn (OR 2.9, 95% CI 1.2–6.9). Conclusion. Morphological characteristics of the placenta are prognostic markers for the development of critical conditions with the APGAR score at birth < 4 points.