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Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
Author(s) -
Ivan Puhar,
Darko Božić,
Domagoj Žabarović,
Damir Jelušić,
Darije Plančak
Publication year - 2015
Publication title -
acta stomatologica croatica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 9
eISSN - 1846-0410
pISSN - 0001-7019
DOI - 10.15644/asc49/2/9
Subject(s) - medicine , periodontitis , aplastic anemia , pancytopenia , anemia , aggressive periodontitis , surgery , gastroenterology , dentistry , bone marrow
Aplastic anemia is a hematological disorder characterized by pancytopenia. This case report presents a young patient with untreated periodontitis associated with hematological disorders, and cyclosporine therapy. During 2 consecutive days, periodontal therapy which consisted of nonsurgical therapy supplemented with an antibiotic treatment and antifibrinolytic therapy was performed. Commercial microbiological PCR tests and periodontitis IL-1 polymorphism risk test were performed. Following the periodontal therapy, the inflammation was resolved and the patient's occlusion was restored by means of removable partial dentures. After the 5 year follow-up, the patient still remained with shallow probing depths although there was inadequate compliance during the maintenance phase. Aplastic anemia increases the risk of onset of severe forms of periodontitis that can be additionally complicated with cyclosporine therapy. In such patients, periodontal therapy must be supplemented with antibiotics.

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