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Triterpenoid và flavonoid từ dịch chiết etyl axetat của cây Nàng nàng ( Callicarpa candicans (Burm. f.) Hochr.) Ở Việt Nam
Author(s) -
Lê Vũ Thị Thu,
Lâm Đỗ Tiến,
Ính Cầm Thị,
Long Phạm Quốc,
Thạch Trần Đăng,
Vân Nguyễn Thị Hồng,
Minh Phạm Thị Hồng
Publication year - 2018
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.15625/vjc.2018-0030
Subject(s) - traditional medicine , flavonoid , triterpenoid , chemistry , stereochemistry , medicine , organic chemistry , antioxidant
Callicarpa candicans (Burm. f.) Hochr. is used in Vietnamese traditional medicine for the treatment of several diseases such as a tonic for new mothers, helps muscles strong, as drugs to treat some diseases of the liver, stomach pain, cure pimples, ulceration. Phytochemical investigation of the ethyl acetate extract of C. candicans led to the isolation of three terpenoids, ursolic acid ( 1 ) as the main compound, 2α‐hydroxy‐ursolic acid ( 2 ), 2α,3β,23‐trihydroxyurs‐12‐en‐28‐oic acid ( 3 ), genkwanin ( 4 ) isolated for the first time from plant and luteolin‐7‐O‐β‐D‐glucopyranoside ( 5 ). Their chemical structures were determined by spectroscopic methods including MS, 1D, 2D NMR and comparing with those reported in previous papers.