Open AccessEVALUATION OF STERCULIA FOETIDA L. GUM AS NATURAL BASED CONTROLLED RELEASE EXCIPIENT
Author(s) -
Thi Hong Quan Vu,
Nguyen Thi Quan,
Mai Thanh Phong,
Le Thi Kim Phung
Publication year - 2019
Publication title -
vietnam journal of science and technology/science and technology
Language(s) - English
Resource type - Journals
eISSN - 2815-5874
pISSN - 2525-2518
DOI - 10.15625/2525-2518/57/3/13323
Subject(s) - excipient , swelling , solubility , chemistry , polysaccharide , materials science , chromatography , composite material , organic chemistry
Therefore, the physicochemical properties of Sterculia foetida L. gum, including solubility, scanning electron micrographs, melting point, swelling index, pH, viscosity, loss on drying were determined. Furthermore, compressed tablets were successfully prepared for in vitro studies at many different particle sizes, concentrations of gum, rotational speeds and media in order to evaluate the effects of these parameters on the rate of drug release. Besides, SFG tablets were compared with the tablets prepared with Hydroxymethylcellulose E15. The findings indicated that Sterculia foetida L. gum exhibited an excellent potential in managed release dosage forms.