Open AccessSTUDY ON CHEMICAL CONSTITUENT AND BIOACTIVITIES OF THE FRUITS OF DIPTEROCARPUS RETUSUS BLUME. DIPTEROCARPACEAE OF VIETNAM
Author(s) -
Ho Dac Hung,
Doan Huy Tien,
Nguyen Thi Ngoan,
Ba Thi Duong,
Do Quoc Viet,
Pham Gia Dien,
Bui Kim Anh
Publication year - 2019
Publication title -
vietnam journal of science and technology/science and technology
Language(s) - English
Resource type - Journals
eISSN - 2815-5874
pISSN - 2525-2518
DOI - 10.15625/2525-2518/57/3/13249
Subject(s) - dipterocarpaceae , ethyl acetate , chemical constituents , column chromatography , chemistry , traditional medicine , butanol , hexane , chemical structure , botany , organic chemistry , chromatography , biology , ethanol , medicine
The first study on chemical constituents and biological activities of fruits of Dipterocarpus retusus Blume (Dipterocarpaceae.) growing in Vietnam was reported. Column chromatography of the ethyl acetate extract led to the isolation of five compounds: eleutherol (1), 3, 5, 4' - trihydroxy - trans - stilbene (2), polydatin (3) and β-sitosterol (4), β-sitosterol-3-O-β-D-glucopyranoside (5). Their structures were elucidated based on the NMR spectroscopic methods and comparison with literature date. The extracts from fruits of D. retusus Blume by n-hexane, ethyl acetate and butanol, consecutively, were evaluated for antioxidative and cytotoxic activities.