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Three‐dimensional Total Synchronous Luminescence Spectroscopy Criteria for Discrimination Between Normal and Malignant Breast Tissues
Author(s) -
Dramićanin Tatjana,
Dramićanin Miroslav D.,
Jokanović Vukoman,
NikolićVukosavljević Dragica,
Dimltrijević Bogomir
Publication year - 2005
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1562/2005-02-15-ra-442
Subject(s) - luminescence , spectroscopy , wavelength , materials science , spectral line , breast cancer , excitation , derivative (finance) , analytical chemistry (journal) , nuclear magnetic resonance , optics , chemistry , cancer , optoelectronics , physics , medicine , chromatography , quantum mechanics , astronomy , financial economics , economics
Specimens of malignant and normal female human breast tissues were analyzed after surgery by means of synchronous luminescence spectroscopy. Measurements were performed in the ranges of excitation wavelengths from 330 to 650 nm and synchronous wavelengths from 30 to 120 nm to obtain ordinary and first derivative three‐dimensional total synchronous luminescence spectra (3d‐TSLS) of each specimen. Arithmetic mean of these spectra has been calculated for normal and malignant specimens and analyzed to establish criteria for tissue differentiation. Spectral domain volumes (volumes below luminescence intensity surface) and mean spectral slopes have been calculated and also analyzed as tissue discrimination criteria. The obtained results are discussed in view of the possible relevance of synchronous luminescence spectroscopy in discrimination between normal and malignant breast tissue.