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Pothomorphe umbellata Extract Prevents α‐Tocopherol Depletion After UV‐irradiation
Author(s) -
Ropke Cristina D.,
Meirelles Renata R.,
Da Silva Vanessa V.,
Sawada Tânia C. H.,
Barros Silvia B. M.
Publication year - 2003
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1562/0031-8655(2003)0780436pueptd2.0.co2
Subject(s) - antioxidant , superoxide dismutase , catalase , chemistry , glutathione reductase , hairless , ascorbic acid , tocopherol , glutathione , glutathione peroxidase , biochemistry , vitamin e , enzyme , food science
In this work we evaluated the influence of topical application of P. umbellata root extract gel, containing 0.1% of 4‐nerolidylcathecol, on the antioxidant network in UV‐induced oxidative damage in hairless mouse skin. The UV‐irradiation had no influence on ascorbic acid levels or on the antioxidant enzyme (superoxide dismutase, catalase, glutathione reductase and glutathione peroxidase) activities, but topical P. umbellata treatment protected α‐tocopherol from being depleted after UV‐irradiation. α‐Tocopherol concentration decreased significantly (∼40%, P < 0.01) in the irradiated control groups, whereas in the P. umbellata –treated group, α‐tocopherol was totally preserved (∼100%, P > 0.05). These data demonstrate that P. umbellata may be successfully used as a topical photoprotective agent.