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A Beam‐splitting Device for Use with Fiber‐coupled Laser Light Sources for Photodynamic Therapy ¶
Author(s) -
Wood Leroy M.,
Bellnier David A.,
Oseroff Allan R.,
Potter William R.
Publication year - 2002
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1562/0031-8655(2002)0760683absdfu2.0.co2
Subject(s) - multi mode optical fiber , photodynamic therapy , optics , materials science , optical fiber , laser , optical power , optoelectronics , diaphragm (acoustics) , numerical aperture , aperture (computer memory) , beam (structure) , fiber , physics , chemistry , wavelength , organic chemistry , acoustics , loudspeaker , composite material
A device that divides light into eight, four or two beams of equivalent power with only minor total power loss was designed, built and tested. The apparatus accepts light from a 200 μm diameter, 0.16 numerical aperture, silica–silica multimode optical fiber connected to one of several laser light sources for photodynamic therapy (PDT) of cancer. The incorporation of a variable iris diaphragm into the optical couplers allows the power of the beams to be independently set. Each of the beams can be coupled to a 400 or 600 μm diameter optical fiber to deliver the therapeutic light to the patient. This device is used in our institute for PDT of patients with either numerous small malignant tumors or single tumors with large surface area.