Premium
Photosensitization of Hypomycin B—A Novel Perylenequinonoid Pigment with Only One Intramolecular Hydrogen Bond ¶
Author(s) -
Zhang HongYu,
Liu Wei,
Liu WeiZhong,
Xie JinLun
Publication year - 2001
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1562/0031-8655(2001)0740191pohban2.0.co2
Subject(s) - intramolecular force , photochemistry , chemistry , photosensitivity , pigment , electron paramagnetic resonance , excited state , hydrogen bond , absorption (acoustics) , fluorescence , stereochemistry , molecule , organic chemistry , materials science , nuclear magnetic resonance , optoelectronics , optics , physics , nuclear physics , composite material
Electron spin resonance technique and spin‐trapping methods were used to determine the photoproduction of 1 O 2 and O 2 ·− by hypomycin B (HMB), a novel perylenequinonoid pigment (PQP) possessing only one hydroxyl group. It was found that the yields of 1 O 2 and O 2 ·− for HMB were comparable to those for hypocrellin A, a typical natural PQP with good photosensitivity. In addition, the absorption and fluorescence spectra for HMB were investigated. The pKa values in the ground and excited states of HMB were determined to be 8.94 and 5.54, respectively. Thus, the photodynamic mechanisms of HMB may involve not only the photogeneration of 1 O 2 and O 2 ·− but also the light‐induced acidification. Consequently, HMB is proposed to be a good photodynamic therapeutic agent.