Premium
Near‐Infrared Two‐Photon Excitation of Protoporphyrin IX: Photodynamics and Photoproduct Generation ¶
Author(s) -
Goyan Rebecca L.,
Cramb David T.
Publication year - 2000
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1562/0031-8655(2000)0720821nitpeo2.0.co2
Subject(s) - protoporphyrin ix , infrared , photochemistry , excitation , protoporphyrin , two photon excitation microscopy , chemistry , optics , physics , photodynamic therapy , porphyrin , organic chemistry , quantum mechanics
The spectroscopy and photochemistry of protoporphyrin IX in ethanol and in Triton X‐100 micelle solution have been examined using near‐infrared two‐photon excitation (TPE). TPE will allow photodynamic therapy with highly localized light dosage. We have determined that the photochemistry subsequent to TPE is very similar to that found for one‐photon excitation. Moreover, the photoproducts observed possess very intense TPE fluorescence spectra, which allows their detection at low relative concentrations.