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NMR Studies of Diffusion‐Coherence Phenomena in Red Cell Suspensions: Current Status
Author(s) -
Regan David G.,
Kuchel Philip W.
Publication year - 2003
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1560/cxgv-j4h5-n5pw-m7de
Subject(s) - chemistry , coherence (philosophical gambling strategy) , diffusion , pulsed field gradient , current (fluid) , chemical physics , statistical physics , nuclear magnetic resonance , spin echo , analytical chemistry (journal) , computational physics , molecule , physics , thermodynamics , magnetic resonance imaging , chromatography , quantum mechanics , medicine , organic chemistry , radiology
Pulsed field‐gradient spin‐echo (PGSE) nuclear magnetic resonance (NMR) diffusion experiments conducted on some heterogeneous systems have been observed to show periodicities in the data. These “coherence patterns” are manifest in the normalized PGSE signal intensities as a function of the spatial wave vector q in so‐called q ‐space plots. The sample that to our knowledge best reveals these coherence patterns is suspensions of red blood cells (RBC). The origin of these patterns and their mathematical and physical underpinnings are now well established. We have used computer simulations of molecular diffusion in lattices of RBC and other cells to aid in the interpretation and analysis of the corresponding experimental data. The aim of this review is to present the current status of NMR q ‐space studies of RBC suspensions that show the diffusion‐coherence effect.