lnc-THRIL and miR-125b relate to disease risk, severity, and imbalance of Th1 cells/Th2 cells in allergic rhinitis | Zendy

Ji Ah Song | Zendy; Dan Liu | Zendy; Weizhi Yin | Zendy

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lnc-THRIL and miR-125b relate to disease risk, severity, and imbalance of Th1 cells/Th2 cells in allergic rhinitis

Author(s) -

Ji Ah Song,

Dan Liu,

Weizhi Yin

Publication year - 2022

Publication title -

allergologia et immunopathologia

Language(s) - English

Resource type - Journals

eISSN - 1578-1267

pISSN - 0301-0546

DOI - 10.15586/aei.v50i3.528

Subject(s) - medicine , rhinorrhea , immune system , immunology , disease , itching , real time polymerase chain reaction , microrna , proinflammatory cytokine , nasal congestion , gastroenterology , inflammation , nose , gene , biochemistry , chemistry , anatomy

Tumor necrosis factor and HNRNPL-related immunoregulatory long noncoding RNA (lnc-THRIL) and its target microRNA (miR)-125b are reported to regulate immune response through several means by participating in allergic rhinitis (AR) pathology. This study aimed to investigate the role of lnc-THRIL and miR-125b in detecting AR risk, and to further explore their correlation with disease severity and cytokines released from T helper type (Th) 1 and Th2 in AR patients.

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