Desensitization to drugs in children
Author(s) -
Luís Felipe Ensina,
Mara Morelo Rocha Félix,
Fernanda Sales da Cunha,
JeanChristoph Caubet
Publication year - 2022
Publication title -
allergologia et immunopathologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 37
eISSN - 1578-1267
pISSN - 0301-0546
DOI - 10.15586/aei.v50i2.539
Subject(s) - medicine , desensitization (medicine) , intensive care medicine , nonsteroidal , drug , pharmacology , receptor
Better knowledge and understanding about drug desensitization is required in the pediatric population, since there is little literature available about it and the most pediatric desensitization protocols have been adapted from adult instructions.Aiming to soften this issue and foster the future studies, this article presents a recent review about mechanisms of desensitization, diagnostic tools, and up to date management of drug hypersensitivity reactions in children. Bringing up an overview of pediatric hypersensitivity reactions to chemotherapy, biologic agents, antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines.
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